CATALYSIS OF TRANSAMIDATION REACTIONS BY PROTEOLYTIC ENZYMES
نویسندگان
چکیده
منابع مشابه
Transamidation reactions catalyzed by cathepsin C.
Previous publications from this laboratory (l-3) have described the catalysis of transamidation reactions by the proteinases papain, ficin, and crystalline chymotrypsin. In addition, preliminary experiments were reported on replacement reactions catalyzed by beef spleen cathepsin C, an intracellular endopeptidase of animal tissues, which resembles pancreatic chymotrypsin in its specificity. The...
متن کاملSpecificity of papain-catalyzed transamidation reactions.
In the experiments reported in the present communication, these studies have been extended with special reference to the specificity of the enzyme toward the dipeptide used as replacement agent. It had been suggested (1) that the value of pKz’ of a dipeptide is a determining factor in the efficiency with which it can participate in a transamidation reaction at ‘a given pH. This suggestion has b...
متن کاملProteolytic enzymes.
Leipner, J. and R. Saller (2000). "Systemic enzyme therapy in oncology: effect and mode of action." Drugs 59(4): 769-80. Plant extracts with a high content of proteolytic enzymes have been used for a long time in traditional medicine. Besides proteolytic enzymes from plants, 'modern' enzyme therapy additionally includes pancreatic enzymes. The therapeutic use of proteolytic enzymes is partly ba...
متن کاملProteolytic enzymes of lung.
The lung usually is considered to be a passive tissue whose main function is to permit gaseous diffusion to and from the blood; however, the lung is also an organ of defense. Its phagocytes remove inhaled dust particles and bacteria. A considerable part of the lung parenchyma consists of mononuclear phagocytes and potential mononuclear phagocytes. Since these cells are not readily available in ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1950
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)56350-x